Thursday, October 20, 2016

Papain/Urea Foam


Pronunciation: pa-PAY-in/ue-REE-a
Generic Name: Papain/Urea
Brand Name: Paptase


Papain/Urea Foam is used for:

Removing dead tissue and thinning the pus in lesions such as ulcers, burns, wounds, and carbuncles.


Papain/Urea Foam is a debriding agent. It works by helping the breakdown of dead skin and pus, which helps improve the recovery time of open wounds.


Do NOT use Papain/Urea Foam if:


  • you are allergic to any ingredient in Papain/Urea Foam

Contact your doctor or health care provider right away if any of these apply to you.



Before using Papain/Urea Foam:


Some medical conditions may interact with Papain/Urea Foam. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Papain/Urea Foam. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Hydrogen peroxide or medicines containing silver, lead, or mercury because they may decrease Papain/Urea Foam's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Papain/Urea Foam may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Papain/Urea Foam:


Use Papain/Urea Foam as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Cleanse the affected area with saline or another mild wound cleansing solution each time the dressing is changed. Do not use hydrogen peroxide.

  • Shake well before each use.

  • You must prime the pump before you use it for the first time. Hold the can upright, pointed away from yourself and others. Push down the actuator until the foam begins to come out.

  • The spray canister will work best if you hold it upright while you apply Papain/Urea Foam; however, you may hold the canister at an angle if necessary.

  • Apply Papain/Urea Foam directly onto the wound or onto a secondary dressing as directed by your doctor.

  • Apply Papain/Urea Foam in a single layer as directed by your doctor. Completely cover the wound with medicine. Cover with appropriate dressing (eg, bandages) and secure into place.

  • Wipe the nozzle with clean gauze after each use.

  • Change wound dressings according to the schedule set by your doctor.

  • If irritation occurs, talk with your doctor about changing the dressings more often.

  • Protect the normal skin around the wound with a skin protectant as directed by your doctor.

  • If you miss a dose of Papain/Urea Foam, use it as soon as you remember. Continue to use it as directed by your doctor.

Ask your health care provider any questions you may have about how to use Papain/Urea Foam.



Important safety information:


  • Papain/Urea Foam is for external use only. Do not get it in your eyes, nose, or mouth. If you get it in any of these areas, rinse right away with cool water.

  • Do not puncture, break, or burn the canister, even if it appears to be empty.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Papain/Urea Foam while you are pregnant. It is not known if Papain/Urea Foam is found in breast milk. If you are or will be breast-feeding while you use Papain/Urea Foam, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Papain/Urea Foam:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Mild skin irritation; temporary burning sensation.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe or persistent skin irritation.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Papain/Urea side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Papain/Urea Foam:

Store Papain/Urea Foam upright, in a cool place, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat and direct sunlight. Avoid temperatures above 120 degrees F (49 degrees C). Do not puncture, break, or burn the canister even if it appears to be empty. Do not freeze. Keep Papain/Urea Foam out of the reach of children and away from pets.


General information:


  • If you have any questions about Papain/Urea Foam, please talk with your doctor, pharmacist, or other health care provider.

  • Papain/Urea Foam is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Papain/Urea Foam. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Papain/Urea resources


  • Papain/Urea Side Effects (in more detail)
  • Papain/Urea Use in Pregnancy & Breastfeeding
  • Papain/Urea Drug Interactions
  • Papain/Urea Support Group
  • 1 Review for Papain/Urea - Add your own review/rating


Compare Papain/Urea with other medications


  • Burns, External
  • Dermatologic Lesion
  • Wound Cleansing

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